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- Synthesis and antimicrobial activity of Phthalimide derivatives
- Bookcover of Synthesis and antimicrobial activity of Phthalimide derivatives
- Booktitle:
-
Synthesis and antimicrobial activity of Phthalimide derivatives
Antimicrobial activity of new molecules
LAP LAMBERT Academic Publishing (2012-04-22 )
eligible for voucher
- ISBN-13:
978-3-8454-1838-4
- ISBN-10:
- 3845418389
- EAN:
- 9783845418384
- Book language:
- Blurb/Shorttext:
- A series of novel phthalimide derivatives (SV 1-8) have been synthesized and evaluated for antimicrobial activity. The target compounds were prepared by fusion of glycine with phthalic anhydride at 150-155 ºC to afford 2-(1, 3- dioxoisoindolin-2-yl) acetic acid. The compound 2-(1, 3-dioxoisoindolin-2-yl) acetic acid was treated with thionyl chloride in chloroform to afford 2-(1, 3-dioxoisoindolin-2-yl) acetyl chloride which was further treated with substituted phenols in presence of anhydrous potassium carbonate in dry acetone yielded the final compounds (SV1-8). The structures of the target compounds were characterized on the basis of their m.p., TLC, IR and 1H-NMR data. All the target compounds were evaluated for antibacterial and antifungal activity.
- Publishing house:
- LAP LAMBERT Academic Publishing
- Website:
- https://www.lap-publishing.com/
- By (author) :
- Shakir Saleem, Jahangir Alam, Imran Kazmi
- Number of pages:
- 108
- Published at:
- 2012-04-22
- Stock:
- Available
- Category:
- Monographies
- Price:
- 59.78 $
- Keywords:
- Antibacterial activity, Antifungal activity, New molecules
