Bookcover of Studies on the Potential Antidepressant Activity of Cannabinoids
Booktitle:
Studies on the Potential Antidepressant Activity of Cannabinoids
LAP LAMBERT Academic Publishing
(2012-12-06
)
eligible for voucher
ISBN-13:
978-3-8433-8787-3
ISBN-10:
3843387877
EAN:
9783843387873
Book language:
English
Blurb/Shorttext:
Could cannabinoids be antidepressant? chronic administration of the phytocannabinoids (THC, CBD) as well as rimonabant had no antidepressant-like effect in normal rats. However, chronic administration of THC and rimonabant had antidepressant-like effects in the OB-model of depression. Given the emergence of anxiety and depression in patients treated with rimonabant, this opens a debate about the predictive validity of animal models for drug effects in humans