Bookcover of Possible mechanisms of methylmercury neurotoxicity
Booktitle:
Possible mechanisms of methylmercury neurotoxicity
Correlation between The Metabolic Effects of Methylmercury and 5-Oxoprolinease inhibitor on both C6 Glial cells and PC12
LAP LAMBERT Academic Publishing
(2012-06-15
)
eligible for voucher
ISBN-13:
978-3-8465-8550-4
ISBN-10:
3846585505
EAN:
9783846585504
Book language:
English
Blurb/Shorttext:
Different studies reported that glutathione (GSH) play a major role in modulating methylmercury (MeHg) neurotoxicity. Glutathione synthetase deficiency (GSD) and 5- Oxoprolinase deficiencies are two inborn errors of GSH metabolism; which were associated with physiological and pathological features resembling patients with Minamata disease (MD). The present study aimed to investigate whether there are similarities between the metabolic effects of MeHg and 5-oxoprolinase inhibitor (ICA) on both C6 Glial cells and PC12 neurons.