Bookcover of Nigella sativa ameliorates experimental autoimmune encephalomyelitis
Booktitle:

Nigella sativa ameliorates experimental autoimmune encephalomyelitis

Neurobehavioral study on an animal model of Multiple Sclerosis

Scholars' Press (2015-01-22 )

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ISBN-13:

978-3-639-76182-5

ISBN-10:
3639761820
EAN:
9783639761825
Book language:
English
Blurb/Shorttext:
Multiple sclerosis (MS) is an immune mediated, inflammatory demyelinating neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a well-established animal model of MS. MS is considered as one of the most important causes of disability in adults. It is a chronic progressive, potentially disabling disorder with considerable social impact and economic consequences. Unfortunately, it is not currently possible to cure MS, the treatments available up to now have centered their action on the anti-inflammatory and disease course-modifying effect, and the purpose of treatment is to prevent recurrence of relapses and accumulation of disability. In addition, all the approved drugs for MS treatment have potentially serious side effects.Therefore the aim of the present study was to investigate the protective as well as the possible ameliorative effects of N. sativa seeds (a natural non-toxic product) in EAE-induced Wistar female rats.
Publishing house:
Scholars' Press
Website:
http://www.scholars-press.com
By (author) :
Heba Fahmy, Neveen Noor, Nasr Radwan
Number of pages:
136
Published at:
2015-01-22
Stock:
Available
Category:
Medicine
Price:
67.90 €
Keywords:
Inflammation, oxidative stress, Experimental autoimmune encephalomyelitis (EAE), Nigella sativa, Demyelination, Myelin Sheath, transforming growth factor

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