Bookcover of Enhancement of the dissolution of a poorly water soluble drug
Booktitle:

Enhancement of the dissolution of a poorly water soluble drug

LAP LAMBERT Academic Publishing (2013-06-17 )

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ISBN-13:

978-3-659-41176-2

ISBN-10:
3659411760
EAN:
9783659411762
Book language:
English
Blurb/Shorttext:
Up to 40% of new chemical entities discovered by the pharmaceutical industry today are poorly soluble or lipophilic compounds. The solubility issues complicating the delivery of these new drugs also affect the delivery of many existing drugs. Poorly water-soluble drugs show unpredictable absorption, since their bioavailability depends upon the dissolution in the gastrointestinal tract. The dissolution characteristics of poorly soluble drugs can be enhanced by several methods. Among these methods, solid dispersions (SDs) and cyclodextrins (CDs) have been extensively studied to improve solubility, dissolution, and bioavailability of various drugs. The present manuscript reveals the significance and methodology of enhancing solubility of a poorly water soluble drug which can be useful to apply for other poorly water soluble drugs.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Sachin Kumar, Pranav Sharma, Kamal Dua
Number of pages:
112
Published at:
2013-06-17
Stock:
Available
Category:
Education, Occupation, Career
Price:
54.90 €
Keywords:
solid dispersion, Dissolution rate enhancement, Inclusion Complexes, aqueous solubility enhancement

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