Bookcover of Development of solid self nano emulsified tablet of furosemide
Booktitle:

Development of solid self nano emulsified tablet of furosemide

Formulation & Optimization of Solid Selfeulsified Tablet of BCS IV drug furosemide to enhance bioavailability

LAP LAMBERT Academic Publishing (2012-09-17 )

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ISBN-13:

978-3-659-24781-1

ISBN-10:
3659247812
EAN:
9783659247811
Book language:
English
Blurb/Shorttext:
Interest in Lipid Based Drug Delivery (LBDD) is relatively recent and relates to the developments in the past 10 to 15 years, largely driven by the growing need for novel drug delivery systems to deal with the vast majority of the new chemical entities (NCE) that have poor solubility or permeability, to improve the delivery of existing drugs, and for line extensions. Other applications include drug coating for either taste masking or protection of the active, and in sustained release dosage forms. Successful drug design with lipids depends largely on understanding the physical–chemical and physiological factors that promote or inhibit bioavailability. It requires a grasp of not only the drug candidate issues but also the role of the drug delivery system or the potential for drug-excipient interplay in vitro as well as in vivo conditions. Depending on the choice of excipient(s) and formulation techniques, it is possible to obtain a variety of systems including physical mixtures, liquid/solid solutions, solid dispersions, and Self-Micro or Self-Nano Emulsifying Drug Delivery Systems (SMEDDS/SNEDDS). These systems may then be incorporated into tablets by absorbing on to absorbents.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Bhupendra Prajapati, Hitesh K. Patel
Number of pages:
152
Published at:
2012-09-17
Stock:
Available
Category:
Pharmacy
Price:
59.00 €
Keywords:
Furosemide, Self emulsifying drug delivery, increase bioavailabilty, bcs class IV drug, low permeability

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