Bookcover of Determination of Clarithromycin in Pure & Pharmaceutical Formulations
Booktitle:

Determination of Clarithromycin in Pure & Pharmaceutical Formulations

A Spectrophotometric Study

LAP LAMBERT Academic Publishing (2012-11-19 )

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ISBN-13:

978-3-659-30666-2

ISBN-10:
3659306665
EAN:
9783659306662
Book language:
English
Blurb/Shorttext:
A simple and sensitive spectrophotometric method has been developed for the determination of clarithromycin in pure and commercial pharmaceutical formulations. The method involves formation of colored ion-associate complex of clarithromycin with bromothymol blue in acidic media (acetate buffer solution). The colored complex was extracted in chloroform which showed the optimum wavelength at 420 nm. Various conditions such as wavelength, acetate buffer pH, acetate buffer volume, bromothymol blue solution concentration and bromothymol blue solution volume were investigated. At the optimum conditions, the method has been applied for the determination of clarithromycin in commercial pharmaceutical formulations. The investigated spectrophotometric method has numerous advantages, for examples, the use of inexpensive chemicals, sensitivity and reproducibility and can be used as alternatives for routine analysis of clarithromycin.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Waqar Ahmad, Kashif Shahid
Number of pages:
64
Published at:
2012-11-19
Stock:
Available
Category:
Medicine
Price:
49.00 €
Keywords:
Waqar

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