Bookcover of Biological Evaluation Of Some 2-Substituted 4,5-Diphenyl Imidazoles
Booktitle:

Biological Evaluation Of Some 2-Substituted 4,5-Diphenyl Imidazoles

A Synthetic and Biological Approach

LAP LAMBERT Academic Publishing (2014-11-11 )

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ISBN-13:

978-3-659-63272-3

ISBN-10:
3659632724
EAN:
9783659632723
Book language:
English
Blurb/Shorttext:
In this book various 2-substituted 4,5-diphenyl imidazoles were prepared by refluxing benzyl with different aromatic aldehydes. The synthesized compounds were characterized by physical data analysis and spectral analysis. The synthesized compounds exhibited analgesic activity against chemically and thermal noxious stimuli. The analgesic activity was found to be significant on the tail-flick model and on the acetic acid induced writhing model. The anti-inflammatory activity was found to be significant on the Carrageenan-induced paw oedema model compared to control. In the Pheretima posthuma, all the synthesized compounds were found to possess anthelmintic activity. The minimum inhibitory concentration (MIC) of the synthesized compounds for the various microbes was determined.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Satyajit Dutta
Number of pages:
88
Published at:
2014-11-11
Stock:
Available
Category:
Pharmacy
Price:
35.90 €
Keywords:
diclofenac sodium, Anthelmintic, Carrageenan, Diphenyl imidazole, Benzil

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