Bookcover of Benzamide based HDAC inhibitors: Synthetic and biological approach
Booktitle:

Benzamide based HDAC inhibitors: Synthetic and biological approach

LAP LAMBERT Academic Publishing (2015-04-10 )

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ISBN-13:

978-3-659-69356-4

ISBN-10:
3659693561
EAN:
9783659693564
Book language:
English
Blurb/Shorttext:
"Fighting cancer is our goal. We can do it it’s in our soul" Despite recent success toward discovery of more effective anticancer drugs, histone deacetylase (HDAC) inhibition plays an important role for the treatment of cancer. HDACs are the part of extensive member of enzymes that have essential biological role mainly through their inhibiting influence on transcription. In this review, we have mainly focus on benzamide based HDAC inhibitors with their synthesis pathways and their biological screening. This review summarizes synthesis of various benzamide derivatives and their evaluated HDAC inhibitory efficacy in terms of IC50 values.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Mayur K. Vekariya, Rajesh H. Vekariya, Nisha K. Shah
Number of pages:
60
Published at:
2015-04-10
Stock:
Available
Category:
Organic chemistry
Price:
39.90 €
Keywords:
anticancer activity, Synthesis, Benzamide derivatives, HDAC inhibitor, IC50 values, Selectivity

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