Bookcover of Anticancer activity of Casearia esculenta in experimental models
Booktitle:

Anticancer activity of Casearia esculenta in experimental models

Anticancer activity of Casearia esculenta

LAP LAMBERT Academic Publishing (2011-04-06 )

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ISBN-13:

978-3-8443-2819-6

ISBN-10:
384432819X
EAN:
9783844328196
Book language:
English
Blurb/Shorttext:
Increase in scientific investigations into indigenious wealth of herbal medicines gives ample evidence of medicinal plants as sources of drugs. Hepatocellular Carcinoma represents about 4% of all malignancies worldwide.Plants contain chemopreventive agents like phenolic compounds, nitrogen compounds and some other endogenous metabolites, which are rich in antioxidant activity. Thioacetamide, a model hepatotoxicant,initiates hepatocellular necrosis and further hepatocarcinogenesis. Thioacetamide thus produces oxidative stress on liver and causes hepatocellular carcinoma. This oxidative stress can be reversed by the use of antioxidants. Thus, the aim of this work was to evaluate the anticancer activity of hydroalcoholic extract prepared from Casearia esculenta, correlating the biochemical and histological changes in thioacetamide induced hepatocellular carcinoma in female Sprague Dawley rats. This research work should help shed some light on cancer research and experimental model development for hepatocellular carcinoma, and should be especially useful to research scholars, scientists and students working on hepatocellular carcinoma in experimental animals.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Dipti Joshi, Dr.Kala Suhas Kulkarni, Dr.Kishori Apte
Number of pages:
68
Published at:
2011-04-06
Stock:
Available
Category:
Pharmacy
Price:
49.00 €
Keywords:
Hepatocellular Carcinoma, Casearia esculenta, thioacetamide, Hepatocellular carcinoma, Thioacetamide

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