Bookcover of 1,3-Pyrimidine Derivatives
Booktitle:

1,3-Pyrimidine Derivatives

Synthesis and Antimicrobial Activity

LAP LAMBERT Academic Publishing (2012-04-12 )

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ISBN-13:

978-3-8484-8835-3

ISBN-10:
3848488353
EAN:
9783848488353
Book language:
English
Blurb/Shorttext:
There has been growing menace of antibiotic resistance in recent past owing to a number of reasons such as self medication and non-compliance on parts of patients with regard to complete dosage regimen. Medicinal chemists are hard pressed to bring about new molecules to cater to this need. 1,3-pyrimidine derivatives have been explored by a number of scientists worldwide and such these derivatives have emerged potential lead molecules for development of newer antimicrobial moieties. The present work reports the syntheses and evaluation of some 2-(6’-fluorobenzothiazol-2’-ylamino)-4,6-(disubstituted thiouriedo) -1,3-pyrimidine derivatives. Some of the synthesized derivatives showed excellent activity against Gram +ve bacteria Staphyllococcus aureus, Bacillus subtilis, and Gram -ve bacteria Escherichia coli and Pseudomonas aeruginosa. The contents of this book must make an excellent read for those interested in antibiotic research and allied interests.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Anoop Kumar Pathak, Viney Chawla, Shailendra K. Saraf
Number of pages:
116
Published at:
2012-04-12
Stock:
Available
Category:
Organic chemistry
Price:
49.00 €
Keywords:
antimicrobial activity, Fluorobenzothiazole, Pyrimidine derivatives, Phenyl thiourea derivatives

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