Production of AC-225 for Cancer Therapy
An overview of recent research
978-3-639-13843-6
3639138430
232
2009-03-20
79.00 €
eng
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Radium needles that were once implanted into tumours
as a cancer treatment are now obsolete and constitute
a radioactive waste problem, as their half-life is
1600 years. The increasing application of Ac-225 for
cancer therapy indicates the potential need for its
increased production and availability. The reduction
of radium by photonuclear transmutation by bombarding
Ra-226 with high-energy photons from a medical linac
has been investigated. The irradiated needles would
then be processed to remove the Ac-225, which can
then be used for ‘Targeted Alpha Therapy’ (TAT) of
cancer.
The research in this monograph investigates the
possibility of producing of Ac-225 in commercial
quantities, which could potentially reduce obsolete
radioactive material and displace the need for
expensive importation of Ac-225 from the USA and
Russia in the years ahead. Scaled up production of
Ac-225 could theoretically be achieved by the use of
a high current cyclotron or linac.
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