Semaphorin
Growth Cone
978-613-8-70592-5
6138705920
84
2011-11-19
34.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes. They are usually cues to deflect axons from inappropriate regions, especially important in neural system development. The major class of proteins that act as their receptors are called plexins. Every semaphorin is characterised by the expression of a specific region of about 500 amino acids called the sema domain.
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