Обложка Microbial aldolases as C-C bonding enzymes
Название книги:

Microbial aldolases as C-C bonding enzymes

Investigation of structural-functional characteristics and application for stereoselective reactions

VDM Verlag Dr. Müller (2009-09-30 )

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ISBN-13:

978-3-639-20250-2

ISBN-10:
3639202503
EAN:
9783639202502
Язык Книги:
Английский
Краткое описание:
Carbon-carbon bonding enzymes can be attractive alternatives to standard chemical methods by allowing chiral control, taking advantage of mild reaction conditions and minimizing the use of protecting groups in reactions. Fructose-6-phosphate aldolase (FSA) from Escherichia coli catalyses reversibly the cleavage of D-fructose-6-phosphate into dihydroxyacetone (DHA) and D-glyceraldehyde-3-phosphate (GAP). In addition, the enzyme creates new building blocks with 3S, 4R configuration by use of DHA as donor and various aldehydes as acceptor. The goal of this work was to investigate FSA and compare it with the transaldolase from Bacillus subtilis (TALBsu) which is similar both in sequence and structure to FSA (30% identical in amino acid residues). This should help to elucidate relationships between structure and function of both enzymes, and possible applications for FSA and TALBsu for the production of valuable sugars or sugar derivatives.
Издательский Дом:
VDM Verlag Dr. Müller
Веб-сайт:
http://www.vdm-verlag.de
By (author) :
Tomoyuki Inoue
Количество страниц:
140
Опубликовано:
2009-09-30
Акции:
В наличии
Категория:
Биохимия, биофизика
Цена:
59.00 €
Ключевые слова:
C-C bonding enzyme, E.coli, aldolase, structural-functional characteristic, stereoselective reaction, FSA, TAL, fructose-6-phosphate

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