Copertina di Dopamine concentration in mouse intracerebral microdialysis study
Titolo del libro:

Dopamine concentration in mouse intracerebral microdialysis study

A new analytical method to determine Dopamine and Acetylcholine concentration in intracerebral microdialysis

Edizioni Accademiche Italiane (02.05.2014 )

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ISBN-13:

978-3-639-77844-1

ISBN-10:
3639778448
EAN:
9783639778441
Lingua del libro:
Risvolto di copertina:
Dopaminergic neurons located in the ventral midbrain are essential for the control of diverse cognitive and motor behaviors and are associated with multiple psychiatric and neurodegenerative disorders, jointly with drug addiction. Three anatomically and functionally distinct subgroups of midbrain dopaminergic neurons have been identified (A8-A10) which give rise to prominent forebrain projections (i.e. mesostriatal, mesocortical and mesolimbic pathways), each one with a different behavioral role. The mesolimbic pathway is involved in drug addiction and there is overwhelming evidence that most of the drugs of abuse, such as: cocaine, amphetamine and even nicotine, increase dopamine transmission in limbic regions of the brain through different mechanisms. The nucleus accumbens (NAc) is the major target of mesolimbic pathway and dopamine release in this area is stimulated after systemic administration of all addictive drugs in mouse. Quantification of dopamine (DA) concentration in in-vivo intracerebral microdialysis study plays a critical role for determination of the effects of drugs in mesolimbic system. Classically, determination of dopamine concentration in microdialysis samples
Casa editrice:
Edizioni Accademiche Italiane
Sito Web:
https://www.edizioni-ai.com/
Da (autore):
Andrea Bighinati
Numero di pagine:
68
Pubblicato il:
02.05.2014
Giacenza di magazzino:
Disponibile
categoria:
Biologia
Prezzo:
35,90 €
Parole chiave:
Dopamine Acetylcholine Microdialysis Psychostimulant

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