Borítókép a Role of the AAA protease Yme1 in mitochondrial protein quality control - hoz
Könyv címe:

Role of the AAA protease Yme1 in mitochondrial protein quality control

A dual role for the AAA protease Yme1

Südwestdeutscher Verlag für Hochschulschriften (31.07.2013 )

Books loader

Omni badge Érvényes utalvány
ISBN-13:

978-3-8381-3717-9

ISBN-10:
3838137175
EAN:
9783838137179
Könyv nyelve:
angol
Ismertető:
During biogenesis of mitochondria, proteins that are encoded in the nuclear DNA are transported into one of the four different mitochondrial subcompartments, outer membrane, inner membrane, matrix or intermembrane space. Proteins are transported across the mitochondrial membranes in an unfolded state and obtain their mature fold only after specific cleavage and folding steps. In the mitochondrial matrix, an elaborate chaperone system assists this process. However, non of the classical chaperones has been identified in the mitochondrial intermembrane space. Towards identification of unknown, non-classical folding helpers in the intermembrane space, a well-studied model protein was targeted to this mitochondrial subcompartment and its folding analyzed. The folding state of the model substrate and a number of diverse endogenous proteins with functions in oxidative phosphorylation, mitochondrial import and dynamics was found to depend on the presence of the AAA protease Yme1. This study confirms that Yme1 has a dual role as protease and as chaperone and occupies a key position in the protein quality control system of the mitochondrial intermembrane space.
Kiadó:
Südwestdeutscher Verlag für Hochschulschriften
Weboldal:
https://www.svh-verlag.de
Szerezte:
Bernadette Schreiner
Oldalszám:
144
Kiadja:
31.07.2013
Raktárkészlet:
Raktáron
Kategória:
Biokémia, biofizika
Ár:
44,90 €
Kulcsszavak:
S. cerevisiae, Protein folding, mitochondria, chaperones, AAA protease, Yme1, protein quality contol, mitochondrial intermembrane space

Books loader

Adyen::diners Adyen::jcb Adyen::discover Adyen::amex Adyen::mc Adyen::visa Adyen::cup Adyen::alipay Adyen::unionpay Adyen::paypal Paypal Banki átutalás

  0 termékek a bevásárlókosárban
Kosár szerkesztése
Loading frontend
LOADING