Bookcover of Tracing Disease Genes in Non-syndromic Clefts of Orofacial region
Booktitle:

Tracing Disease Genes in Non-syndromic Clefts of Orofacial region

TGF - beta 3 and HLA

LAP LAMBERT Academic Publishing (2015-03-31 )

Books loader

Omni badge eligible for voucher
ISBN-13:

978-3-659-68862-1

ISBN-10:
3659688622
EAN:
9783659688621
Book language:
English
Blurb/Shorttext:
Orofacial clefts are major human birth defects with complex etiology. Previous studies have proposed Transforming growth factor - beta 3 (TGF-B3) gene as one of the important genes in which polymorphisms may contribute to nonsyndromic cleft lip and palate, however none of the studies included Indian population. The HLA [Human leucocyte antigen] loci are the most polymorphic human proteins, and by virtue of their extreme polymorphism ensure that few individuals are identical. Hence HLA typing can be used to identify a subset of population who are at an increased risk of developing or inheriting a particular disease or anomaly. Studies pertaining to the relationship of HLA haplotype and cleft lip and palate are very few and none of these includes Indian patients. This study is a pioneering step towards establishing an association of HLA class I genes and TGFB3 gene with cleft lip and palate in patients of Indian origin.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Saleem Shaikh, Zuber Naqvi, Zameer Pasha
Number of pages:
68
Published on:
2015-03-31
Stock:
Available
Category:
Dentistry
Price:
28.90 €
Keywords:
cleft lip and palate, HLA, TGF-beta 3, Non syndromic

Books loader

Adyen::diners Adyen::jcb Adyen::discover Adyen::amex Adyen::mc Adyen::visa Adyen::cup Adyen::ach Adyen::unionpay Adyen::paypal Paypal Wire Transfer

  0 products in the shopping cart
Edit cart
Loading frontend
LOADING