Bookcover of The blood memory
Booktitle:

The blood memory

Assessment of the chronic myeloproliferative disorders in patients with CML mutations Philadelphia chromosome BCR/ABL1

LAP LAMBERT Academic Publishing (2016-10-26 )

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ISBN-13:

978-3-659-97774-9

ISBN-10:
3659977748
EAN:
9783659977749
Book language:
English
Blurb/Shorttext:
Today the hematological infectious diseases are very important. Dangerous and life-threatening human diseases, such as CML Lukemia is also very important and must do more research Catch. Unfortunately routes now there is no cure for the disease, CML Lukemia, and every year the number of deaths the disease will increase. Genetic studies in the future we hope to be able to cure this disease is very dangerous. In this book, we looked at mutations in chromosomes 9 and 22 and how to switch genes BCR and ABL1 in creating the Philadelphia chromosome, were analyzed.Chronic myeloproliferative disorders (MPDs) are a heterogeneous group of diseases in which a clonal disorder of hematopoietic stem cells leads to an increase in the level of production in one or more of the blood cell. CML Lukemia recently acquired mutations in many patients with chronic myeloproliferative disorders (MPDs) is described by changing G to T mutation at nucleotide 1849 in exon 12 of the JAK2 gene is located on chromosome 9 identified, which leads to substitution of the amino acid phenylalanine instead of valine at position 617 of the protein JAK2.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Shahin Asadi, Mina Niknia
Number of pages:
216
Published on:
2016-10-26
Stock:
Available
Category:
Genetics
Price:
69.90 €
Keywords:
Philadelphia Chromosome, Chronic myeloproliferative disorders(CML), BCR/ABL1 Mutation-9q, 22q ARMS-PCR technique

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