Bookcover of Synthesis and antimicrobial activity of Phthalimide derivatives
Booktitle:

Synthesis and antimicrobial activity of Phthalimide derivatives

Antimicrobial activity of new molecules

LAP LAMBERT Academic Publishing (2012-04-22 )

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ISBN-13:

978-3-8454-1838-4

ISBN-10:
3845418389
EAN:
9783845418384
Book language:
English
Blurb/Shorttext:
A series of novel phthalimide derivatives (SV 1-8) have been synthesized and evaluated for antimicrobial activity. The target compounds were prepared by fusion of glycine with phthalic anhydride at 150-155 ºC to afford 2-(1, 3- dioxoisoindolin-2-yl) acetic acid. The compound 2-(1, 3-dioxoisoindolin-2-yl) acetic acid was treated with thionyl chloride in chloroform to afford 2-(1, 3-dioxoisoindolin-2-yl) acetyl chloride which was further treated with substituted phenols in presence of anhydrous potassium carbonate in dry acetone yielded the final compounds (SV1-8). The structures of the target compounds were characterized on the basis of their m.p., TLC, IR and 1H-NMR data. All the target compounds were evaluated for antibacterial and antifungal activity.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Shakir Saleem, Jahangir Alam, Imran Kazmi
Number of pages:
108
Published on:
2012-04-22
Stock:
Available
Category:
Monographies
Price:
49.00 €
Keywords:
Antibacterial activity, Antifungal activity, New molecules

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