Bookcover of Sulfonamides: X-Ray Structures and Biological Studies
Booktitle:

Sulfonamides: X-Ray Structures and Biological Studies

A new approach towards Biologically Active Compounds

LAP LAMBERT Academic Publishing (2012-06-18 )

Books loader

Omni badge eligible for voucher
ISBN-13:

978-3-659-15531-4

ISBN-10:
3659155314
EAN:
9783659155314
Book language:
English
Blurb/Shorttext:
The use of antibiotics in the treatment of various infections of humans caused by microbes has been a great success. Over the past years there has been an increase in the resistance of microorganisms against a large number of drugs. Keeping in view the biological activity and medicinal importance of sulfonamides, new sulfonamides are being synthesized. This book describes the synthesis of N-benzyl-4-methylbenzenesulfonamide, its N-alkylated derivatives and evaluation of their anti-microbial activity. N-benzyl-4- methylbenzene sulfonamide was synthesized by the condensation of benzyl amine with p-toluene benzenesulfonylchloride. The solvent used for this reaction was water.N-alkylated derivatives were prepared by reacting N-benzyl-4-methylbenzenesulfonamide with different alkylating agents and sodium hydride using DMF as solvent. The synthesized compounds were characterized by different techniques like X-ray crystallography, FT-IR, Elemental analyzer and melting point. Evaluation of anti-microbial activity was carried out by employing deep well method against different bacterial strains.The synthesized compounds exhibited appreciable anti-microbial activity.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Waqar Ahmad, Asia Butt, Islam Ullah khan
Number of pages:
104
Published on:
2012-06-18
Stock:
Available
Category:
Chemistry
Price:
49.00 €
Keywords:
X-ray Crystallography, FT-IR, Elemental analyzer, N-benzyl-4-methylbenzenesulfonamide

Books loader

Newsletter

Adyen::diners Adyen::jcb Adyen::discover Adyen::amex Adyen::mc Adyen::visa Adyen::cup Adyen::alipay Adyen::unionpay Adyen::paypal Paypal CryptoWallet Wire Transfer

  0 products in the shopping cart
Edit cart
Loading frontend
LOADING