Studies on divergent CRP-dependent promoters
978-3-8383-5197-1
3838351975
276
2010-03-18
2,797.39 NT$
eng
https://images.our-assets.com/cover/230x230/9783838351971.jpg
https://images.our-assets.com/fullcover/230x230/9783838351971.jpg
https://images.our-assets.com/cover/2000x/9783838351971.jpg
https://images.our-assets.com/fullcover/2000x/9783838351971.jpg
Bacterial genomes contain genes that are packed closely together. For many genes, promoter regions overlap, and regulatory segments that carry divergent promoters are common. In this study, I have focussed on promoters that are regulated by the cyclic AMP receptor protein (CRP) of Escherichia coli. CRP is a global regulator that directs the activity of more than 100 genes, some of which are oriented back-to-back, i.e., in a divergent fashion. CRP is known to activate transcription initiation through direct protein-protein contact with RNA polymerase and CRP-dependent promoters are classified into two classes, Class I and Class II, according to the location of the CRP-binding site. I have investigated whether a single bound CRP, either at a Class I or a Class II location, can activate divergent transcription.
https://www.morebooks.shop/books/gb/published_by/lap-lambert-academic-publishing/47/products
Genetics
https://www.morebooks.shop/store/gb/book/studies-on-divergent-crp-dependent-promoters/isbn/978-3-8383-5197-1