Bookcover of Studies on divergent CRP-dependent promoters
Booktitle:

Studies on divergent CRP-dependent promoters

LAP LAMBERT Academic Publishing (2010-03-18 )

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ISBN-13:

978-3-8383-5197-1

ISBN-10:
3838351975
EAN:
9783838351971
Book language:
English
Blurb/Shorttext:
Bacterial genomes contain genes that are packed closely together. For many genes, promoter regions overlap, and regulatory segments that carry divergent promoters are common. In this study, I have focussed on promoters that are regulated by the cyclic AMP receptor protein (CRP) of Escherichia coli. CRP is a global regulator that directs the activity of more than 100 genes, some of which are oriented back-to-back, i.e., in a divergent fashion. CRP is known to activate transcription initiation through direct protein-protein contact with RNA polymerase and CRP-dependent promoters are classified into two classes, Class I and Class II, according to the location of the CRP-binding site. I have investigated whether a single bound CRP, either at a Class I or a Class II location, can activate divergent transcription.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Mohamed Elrobh, Prof. Stephen J.W. Busby
Number of pages:
276
Published on:
2010-03-18
Stock:
Available
Category:
Genetics
Price:
79.00 €
Keywords:
Transcription, E coli, CRP, Prokaryotes

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