Bookcover of Significance of nutraceuticals in inhalant abuse
Booktitle:

Significance of nutraceuticals in inhalant abuse

LAP LAMBERT Academic Publishing (2015-03-16 )

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ISBN-13:

978-3-659-40862-5

ISBN-10:
365940862X
EAN:
9783659408625
Book language:
English
Blurb/Shorttext:
Inhalant abuse is the deliberate inhalation of vapor of the inhalants with the intention to alter one's consciousness. Inhalant abuse can result in serious organ system dysfunction and CNS disorder or even sudden death. The present study focuses on evaluating the role of treatment with different neutracenticals including hormones (melatonin), amino acids (tyrosine and tryptophan) and vitamins (folic acid and vitamin B12) against gasoline, perchloroethylene or toluene-induced neurodegenerative damage in adult male rats. The present result revealed that inhalation of gasoline, perchloroethylene or toluene for quarter an hour / day for 45 days led to significant increase in brain lipid peroxidation, GABA levels and plasma DHEA-S concentration. On the other hand, the selected inhalants caused significant depletion in brain glutathione, serotonin, dopamine levels and plasma testosterone, T3 and T4 concentrations. In contrast, the treatment with the different nutraceuticals resulted in pronounced improvement in most of biochemical markers as well as histopathological features of the brain which highlighted the usefulness of these therapies in maintaining the brain function activity.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Soheir E. Kotob, Hanaa H. Ahmed, Mohamed B. Ahmed
Number of pages:
196
Published on:
2015-03-16
Stock:
Available
Category:
Biochemistry, biophysics
Price:
64.90 €
Keywords:
Gasoline, melatonin, Toluene, Tryptophan, Tyrosine, Inhalant abuse, perchloroethylene, folic acid and vitamin B12

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