Bookcover of Saraca indica against Cyclophosphamide induced cardiotoxicity
Booktitle:

Saraca indica against Cyclophosphamide induced cardiotoxicity

A Biochemical, Electrocardiographic and Histopathological Investigation

LAP LAMBERT Academic Publishing (2012-04-07 )

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ISBN-13:

978-3-8484-8091-3

ISBN-10:
3848480913
EAN:
9783848480913
Book language:
English
Blurb/Shorttext:
The study was designed to evaluate the cardioprotective potential of Saraca indica (SI) herb extract on the basis of biochemical, electrocardiographic and histopathological parameters in cyclophosphamide (CP) induced myocardial toxicity. Cardiotoxicity was induced in rats by administering cyclophosphamide (200 mg/kg, i.p.) single injection. SI (200 and 400 mg/kg, p.o.) were administered immediately after administration of cyclophosphamide on first day and daily for 10 days. The general observations, ECG, Level of biomarkers, serum enzymes, Lipid profiles, antioxidant enzymes, level of myocardial infarction & Histopathological changes were estimated. The Reports indicates that Saraca indica treatment produced dose dependent protective effect in ameliorating the biochemical, histopathological and electrographic abnormities caused by CP administration.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Uchit Patel, Sudhir Sojitra, Nikunj Patel
Number of pages:
144
Published on:
2012-04-07
Stock:
Available
Category:
Media sciences
Price:
59.00 €
Keywords:
free radicals, Cardiotoxicity, cardioprotective, Cyclophosphamide, : Antioxidant, Saraca indica.

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