Bookcover of Pyrazolopyrimidine derivatives as cyclin-dependant kinase inhibitors
Booktitle:

Pyrazolopyrimidine derivatives as cyclin-dependant kinase inhibitors

LAP LAMBERT Academic Publishing (2016-02-26 )

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ISBN-13:

978-3-659-79299-1

ISBN-10:
3659792993
EAN:
9783659792991
Book language:
English
Blurb/Shorttext:
This book contains both review and synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as cycline dependent kinase inhibitors (CDKIs). Moreover, cytotoxic activity for the newly synthesized compounds were evaluated, specially on breast cancer cell line (MCF-7). The results obtained were compared with methotrexate as a reference drug. Docking study and molecular modeling were also done using MOE program. I hope this work to be helpful and a starting point for much more new compounds with better activity to help in treatment of such a big terrible disease like cancer. Author: Phoebe F. Lamie
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Phoebe F. Lamie
Number of pages:
248
Published on:
2016-02-26
Stock:
Available
Category:
Organic chemistry
Price:
76.90 €
Keywords:
organic chemistry, PHARMACY

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