Bookcover of Phospholipase A2 inhibitors as anti-inflamatory molecules
Booktitle:

Phospholipase A2 inhibitors as anti-inflamatory molecules

LAP LAMBERT Academic Publishing (2016-04-13 )

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ISBN-13:

978-3-659-86690-6

ISBN-10:
3659866903
EAN:
9783659866906
Book language:
English
Blurb/Shorttext:
Secretory phospholipase A2 is a crucial regulatory enzyme in the initiation of any inflammatory reactions there by producing various pro-inflammatory lipid mediators and reactive oxygen species. Elevateted level of sPLA2 is reported in all pathophysiological conditions. During the healing process this enzyme should be down regulated, other wise the defensive inflammatory reactions become potentially harmful and ends up in various chronic inflammatory disorders which are life threatening. The reactive oxygen species produced during injury and infection that inturn activates PLA2 enzyme by that they worsen the situation to greater extent. Uncontrolled strong stimuli of on going inflammatory reactions are controlled by anti-inflammatory drugs. There are many ways of bringing down inflammation and its damage to the human system. Glucocorticosteroids and non-steroidal anti-inflammatory agents have been used for decades as anti-inflammatory drugs even though they have considerable side effects on the human body. From the clinical studies it has been suggested that inhibitors of inflammatory PLA2 enzymes are therapeutically powerful as anti-inflammatory drugs.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Dharmappa Kattepura Krishnappa
Number of pages:
148
Published on:
2016-04-13
Stock:
Available
Category:
Biochemistry, biophysics
Price:
61.90 €
Keywords:
legumes, Macrotyloma uniflorum, Secretory Phospholipase A2, genestein, oleanolic acid, BIOACTIVE MOLECULES, Human pleural fluid (HPF), Human sinovial fluid (HSF), clerodendron serratum, Glycine Max

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