Bookcover of Pathology of Fluorosis and Prevention
Booktitle:

Pathology of Fluorosis and Prevention

Pathology of Sodium Fluoride Toxicity in rats and its Amelioration with Aloe vera leaf extract

LAP LAMBERT Academic Publishing (2016-09-21 )

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ISBN-13:

978-3-659-94789-6

ISBN-10:
365994789X
EAN:
9783659947896
Book language:
English
Blurb/Shorttext:
The problem of excess fluoride in drinking water is of recent origin in most parts of India. Digging up of shallow aquifers for irrigation has resulted the water from these aquifers contains a higher level of fluoride. Fluorosis is a major public health problem resulting from long-term consumption of water with high fluoride levels may cause dental mottling and skeletal manifestations. In addition to this, chronic fluoride poisoning is cause a variety of pathological changes in soft tissues. The present study mainly focused on the pathology of fluoride toxicity and prevention by herbal product i.e. Aloe vera. In this study toxic changes were noticed mainly in liver, kidney, bone followed by brain and lung indicating the hepatotoxic, nephrotoxic, osteoporotic followed by pulmonary toxic and neurotoxic nature of fluoride. Hyperplastic changes that were noticed in the bile ductular epithelial cells and bronchial epithelial cells indicate that NaF can lead to precancerous changes in long durations. The changes in the spleen and lymph node indicate the immunosuppressive effect of fluoride. In conclusion, the results from present study revealed that sub chronic fluoride toxicity results.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Karamala Sujatha, Avalala Navathej ( Late)
Number of pages:
152
Published on:
2016-09-21
Stock:
Available
Category:
Veterinary medicine
Price:
55.90 €
Keywords:
Amelioration, Fluorosis, pathology, Wistar rats, Aloe vera leaf extract

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