Bookcover of Neuronal Dysfunction Induced by Drugs of Abuse
Booktitle:

Neuronal Dysfunction Induced by Drugs of Abuse

Cellular and Molecular Approach

VDM Verlag Dr. Müller (2009-07-22 )

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ISBN-13:

978-3-639-17669-8

ISBN-10:
3639176693
EAN:
9783639176698
Book language:
English
Blurb/Shorttext:
Substance abuse and addiction are the most costly of all neuropsychiatric disorders. In the last decades, much progress has been achieved in the understanding the effects of the drugs of abuse on the brain. However, efficient treatments that prevent relapse have not been developed. Understanding the mechanisms that underlie brain dysfunction observed in these individuals may contribute to improve the treatment of drug addiction, which may have serious social and economical consequences. This book presents a review of the literature on this subject, as well as studies on the neurotoxic effects of the drugs of abuse amphetamine, cocaine and heroin, exploring their cellular and molecular mechanisms of action, with a focus on oxidative stress and apoptosis. The role of mitochondria and ionotropic glutamate receptors in the neuronal dysfunction induced by these drugs is also explored. This book should be useful to anyone interested in the molecular mechanisms of drug addiction.
Publishing house:
VDM Verlag Dr. Müller
Website:
http://www.vdm-verlag.de
By (author) :
Teresa Cunha-Oliveira
Number of pages:
204
Published on:
2009-07-22
Stock:
Available
Category:
Pharmacy
Price:
49.00 €
Keywords:
Drug addiction, Heroin, cocaine, amphetamine, Cell Biology, neurotoxicity, apoptosis, oxidative stress, NMDA receptors, cell death

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