NAD+ analogues as colorigenic and fluorogenic chemical probes for NAD+ consuming enzymes
AV Akademikerverlag
(2015-04-02
)
eligible for voucher
ISBN-13:
978-3-639-80687-8
ISBN-10:
3639806875
EAN:
9783639806878
Book language:
English
Blurb/Shorttext:
NAD+ consuming enzymes play an important role in fundamental cellular processes and have been shown to be involved in various diseases and the extension of lifespan. To understand underlying mechanisms and to find potential enzyme activators or inhibitors, the approach of chemical probes has proven to be successful on some enzymes, but broadening the applicability and discovering new probes is still an important goal.