Bookcover of Molecular Markers in Acute Myeloid Leukemia (AML)
Booktitle:

Molecular Markers in Acute Myeloid Leukemia (AML)

Significance of Molecular Markers for Patients in the Intermediate Risk Group

AV Akademikerverlag (2016-08-30 )

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ISBN-13:

978-3-330-50542-1

ISBN-10:
3330505427
EAN:
9783330505421
Book language:
English
Blurb/Shorttext:
Acute myeloid leukemia is a malignant disease of the hematopetic system. It often leads to a massive proliferation of precoursors of myelopoiesis in the bone marrow and blood. Based on the morphology of the immature blood cells and their differentiation AMLs are stratificated into eight sub-goups using the French-American-British classification (FAB). Despite classification, generating a prognosis for the patient is often difficult, which in turn makes the selection of the appropriate treatment more difficult. Prognosis is mainly based upon age, white-cell count and on cytogenetics of patients. The cytogenetic classification into the risk groups favorable, intermediate and unfavorable determines the intensity of therapy. In the intermediate group most patients have a normal karyotype, but their progress of disease is very variable. For this reason it is intended to search for novel prognostic, molecular markers which give a more accurate prediction of the progression of disease.
Publishing house:
AV Akademikerverlag
Website:
http://www.akademikerverlag.de/
By (author) :
Iris Pöll
Number of pages:
84
Published on:
2016-08-30
Stock:
Available
Category:
Genetics
Price:
28.90 €
Keywords:
Molecular Markers, AML, acute myeloid leukemia, FLT3, NPM1, BAALC, ERG, MN1, c-KIT

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