Bookcover of Microemulsion- A novel drug delivery system
Booktitle:

Microemulsion- A novel drug delivery system

A Novel approach for treatment of psoriasis by topical drug delivery

LAP LAMBERT Academic Publishing (2012-05-22 )

Books loader

Omni badge eligible for voucher
ISBN-13:

978-3-659-12486-0

ISBN-10:
3659124869
EAN:
9783659124860
Book language:
English
Blurb/Shorttext:
Purpose of the study is to develope stable Methotrexate (MTX) loaded Microemulsion based formulation for topical treatment of Psoriasis with improvement in cutaneous deposition and to enhance the local effect. Several treatments of psoriasis are available, each specifically related to certain factors but none of these have curative effects. For practical purposes, patients with less than 15 % body surface involvement can be treated effectively with topical agents. In last few decades there is increasing in understandings of skin & its barrier properties which allowed development of more efficient means of delivering drugs through skin. Methotrexate has been shown to selectively inhibit DNA synthesis in psoriatic epidermal cells, thus decreasing mitotic activity. Localization of MTX in effected layers of skin is likely to improve the role of topical dosage form of drug as a supplementary to oral therapy for treatment of psoriasis. In recent years, Microemulsion is recognized as one good vehicle for the percutaneous absorption of drugs. So in present study, attempt was made for finding powerful formulation of poorly soluble MTX for topical treatment of Psoriasis.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Nirmal Shah, Avinashkumar Seth, Chintan Aundhia
Number of pages:
128
Published on:
2012-05-22
Stock:
Available
Category:
Pharmacy
Price:
59.00 €
Keywords:
Psoriasis, microemulsion, Methotrexate, Topical delivery

Books loader

Newsletter

Adyen::diners Adyen::jcb Adyen::discover Adyen::amex Adyen::mc Adyen::visa Adyen::cup Adyen::unionpay Adyen::paypal Paypal CryptoWallet Wire Transfer

  0 products in the shopping cart
Edit cart
Loading frontend
LOADING