Bookcover of Immunity to HIV Vaccine Peptides
Booktitle:

Immunity to HIV Vaccine Peptides

HIV Immunity to Vaccine Peptides in High-Risk Volunteers

LAP LAMBERT Academic Publishing (2013-10-03 )

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ISBN-13:

978-3-659-45860-6

ISBN-10:
3659458600
EAN:
9783659458606
Book language:
English
Blurb/Shorttext:
The continuing HIV/ AIDS pandemic represent one of the greatest challenges for researchers and clinicians. This book gives an overview of HIV epidemiology and virology while discussing high-risk behavior factors, HIV immunity and diagnosis. The author argues that vaccine studies usually require volunteers who are followed over a long period of time. She further shows that a high risk cohort of exposed seronegative individuals, that was studied in Nairobi - Kenya, could provide background data for planning HIV-1 Phase II and III vaccine trials. The book discusses challenges encountered in the follow-up of such a cohort in a developing country where such studies have not been done before. The author also explains that the measurement of cellular immunogenicity by interferon gamma Elispot assay in exposed seronegative individuals was not effective. Consequently, there is need to improve the assay or use it in combination with other assays. This book is recommended to students and researchers in biomedical sciences especially those interested in HIV vaccinology.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Margaret Muturi
Number of pages:
116
Published on:
2013-10-03
Stock:
Available
Category:
Medicine
Price:
54.90 €
Keywords:
epidemiology, HIV/ AIDS, High-Risk Behavior Factors, Seronegative Cellular Immunogenicity, Interferon Gamma Elispot Assay, Vaccinology, Virology

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