Bookcover of Fast Release Rabeprazole Sodium Tablet Using Acid-buffer Technology

Booktitle:

Fast Release Rabeprazole Sodium Tablet Using Acid-buffer Technology

Formulation and optimization of fast release tablet

LAP LAMBERT Academic Publishing (2012-04-10 )

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ISBN-13:: 978-3-8484-8529-1
ISBN-10:: 384848529X
EAN:: 9783848485291
Book language:: English
Blurb/Shorttext:: The present invention is aimed to formulate the “non-enteric” formulation of immediate release rabeprazole sodium tablet using acid-buffer technology. The formulation comprising the core tablet containing rabeprazole sodium compression coated with buffer containing super disintegrant. The coat formulation disintegrates fast which provide the higher pH environment then the core formulation gives drug release so degradation of rabeprazole sodium can prevent. From the above perception, the invention is aimed: 1.To study the pH stability of rabeprazole sodium in at different pH medium. 2.To select the proper buffer combination for better basic environment. 3.To formulate the fast release compression coated tablet of rabeprazole sodium. 4.To optimize the formulation using suitable experimental design.
Publishing house:: LAP LAMBERT Academic Publishing
Website:: https://www.lap-publishing.com/
By (author) :: Alpesh D. Patel, Girish Patel, Natvarlal Patel
Number of pages:: 104
Published on:: 2012-04-10
Stock:: Available
Category:: Pharmacy
Price:: 49.00 €
Keywords:: Compressed Coated, Acid Buffer Technology, and Modified Fuchs Model