Bookcover of Endometrial receptors mediate spheroids-endometrium attachment
Booktitle:

Endometrial receptors mediate spheroids-endometrium attachment

Plexin B1, c-Met and Progesterone receptor A mediate spheroids-endometrium attachment

VDM Verlag Dr. Müller (2009-07-09 )

Books loader

Omni badge eligible for voucher
ISBN-13:

978-3-639-17554-7

ISBN-10:
3639175549
EAN:
9783639175547
Book language:
English
Blurb/Shorttext:
Implantation in humans involves cross talk between an active blastocyst and receptive endometrium. The role of the endometrial receptors in this complex embryo-maternal interaction is still unclear. We tested gene and protein expression of endometrial receptors (Plexin-B1, c-Met and Progesterone receptor A) and the effect of these receptors in endometrial receptivity. Methods: Two endometrial cell lines were used: HEC-1A and RL95-2 considered as being of low and high receptivity, respectively. Western blot and RT-PCR analysis were utilized to study the receptor expression profile. The role of endometrial receptors in endometrial receptivity was studied by attachment and invasion assays of JAR spheroids on endometrial cells. Different manipulations of inhibition and stimulation of the endometrial receptors were used. Conclusion: Differential endometrial receptor profiles are expressed during the receptivity period. The attachment and invasion processes are separately regulated. We suggest a biologically functional role for PB1, PRA and the complex PB1-c- MET in endometrial receptivity and in the attachment process.
Publishing house:
VDM Verlag Dr. Müller
Website:
http://www.vdm-verlag.de
By (author) :
Dr. Haggar Harduf
Number of pages:
60
Published on:
2009-07-09
Stock:
Available
Category:
Microbiology
Price:
49.00 €
Keywords:
"Implantation", "Receptivity", "Endometrium" "Plexin B1", "Progesterone receptor A", "c-MET", "Attachment", "Progesterone receptor A"

Books loader

Adyen::diners Adyen::jcb Adyen::discover Adyen::amex Adyen::mc Adyen::visa Adyen::cup Adyen::unionpay Adyen::paypal Paypal Wire Transfer

  0 products in the shopping cart
Edit cart
Loading frontend
LOADING