Bookcover of Dopaminergic control of the globus pallidus
Booktitle:

Dopaminergic control of the globus pallidus

And its impact on the subthalamic nucleus and the pars reticulata of substantia nigra

Noor Publishing (2016-09-15 )

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ISBN-13:

978-3-330-79603-4

ISBN-10:
3330796030
EAN:
9783330796034
Book language:
English
Blurb/Shorttext:
This book is a part of integrative neurobiology and focuses on studying the control exerted by dopamine on basal ganglia (BG), especially the external part of globus pallidus or GPe; GPe being a nucleus, which plays a key role in the control of movement by exerting an inhibitory influence on the output structures of the BG circuitry. The action of dopamine is mediated by D2 receptors that modulate neuronal activity of this nucleus that receives direct dopaminergic projections from the substantia nigra compacta (SNc). Using appropriate pharmacological tools (dopamine and its agonist/antagonist), we studied, in the rat, the effects of dopamine on modulating the basal activity of GPe neurons and its impact on the two major efferent structures, the subthalamic nucleus (STN) and the pars reticulata of substantia nigra (SNr) using an extracellular electrophysiological approach combined with local intracerebral microinjection of drugs in vivo.
Publishing house:
Noor Publishing
Website:
https://www.noor-publishing.com
By (author) :
Omar Mamad
Number of pages:
156
Published on:
2016-09-15
Stock:
Available
Category:
Biology
Price:
409.94 HK$
Keywords:
Neuroscience, basal ganglia, Globus pallidus, STN, SNr, Dopamine, Rat

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