Bookcover of Design and evaluation of prolonged release gliclazide matrix tablets
Booktitle:

Design and evaluation of prolonged release gliclazide matrix tablets

Prolonged Release Gliclazide Matrix Tablet

LAP LAMBERT Academic Publishing (2012-06-04 )

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ISBN-13:

978-3-659-14410-3

ISBN-10:
365914410X
EAN:
9783659144103
Book language:
English
Blurb/Shorttext:
In the present study an attempt has been made to evaluate the effect of hydrophilic polymers on the release profile of drug from matrix system. Matrix tablets of Gliclazide were prepared by both direct compression and wet granulation process using METHOCEL K15M CR, METHOCEL K4M CR, METHOCEL E4M CR and HYPROMELLOSE 15cps.Release kinetics of Gliclazide from these extended release matrices at Phosphate buffer (pH 7.4) using USP paddle method was conducted for 10 hours and examined. Statistically significant differences were found among the drug release profile from different classes of polymeric matrices, polymer concentration and granulation process.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Tanbir Ahammad, Saki Sultana
Number of pages:
276
Published on:
2012-06-04
Stock:
Available
Category:
Pharmacy
Price:
79.00 €
Keywords:
Gliclazide, Matrix Tablet, Prolonged release

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