Bookcover of Cultivation medium optimization for Cyclosporin 'A' production
Booktitle:

Cultivation medium optimization for Cyclosporin 'A' production

Modification of carbon and nitrogen sources in fermentation medium for production of Cyclosporin A by Aspergillus terreus

VDM Verlag Dr. Müller (2011-08-23 )

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ISBN-13:

978-3-639-37781-1

ISBN-10:
3639377818
EAN:
9783639377811
Book language:
English
Blurb/Shorttext:
Cyclosporin 'A' is a cyclic peptide and was originally isolated from a soil fungus. The compound is typically used to reduce the body's natural immunity in patients who receive kidney, liver and heart transplants and can also be used to treat severe cases of psoriasis and rheumatoid arthritis diseases. Cyclosporin 'A' is in common usage for kidney and other organ transplants as an anti-rejection medicine. So its importance can not be denied. In the present work, nine local strains of Aspergillus terreus were tested for the production of Cyclosporin 'A' and one best among them was selected for further study. The composition of cultivation medium highly affects the metabolite production by fungi, so carbon and nitrogen sources were optimized for the cultivation medium using the selected strain of Aspergillus terreus. The estimation of extracted Cyclosporin 'A' was carried out through HPLC (High Performance Liquid Chromatography).
Publishing house:
VDM Verlag Dr. Müller
Website:
http://www.vdm-verlag.de
By (author) :
Sundas Tanseer, Tehmina Anjum
Number of pages:
96
Published on:
2011-08-23
Stock:
Available
Category:
Microbiology
Price:
49.00 €
Keywords:
Cyclosporin A, Aspergillus terreus, Cultivation medium, HPLC(High performance liquid chromatography)

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