Bookcover of Cell-Based Therapy For Chronic Neuropathic Pain After CNS Injury
Booktitle:

Cell-Based Therapy For Chronic Neuropathic Pain After CNS Injury

A Neurophysiological Outlook

LAP LAMBERT Academic Publishing (2011-04-01 )

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ISBN-13:

978-3-8443-2697-0

ISBN-10:
3844326979
EAN:
9783844326970
Book language:
English
Blurb/Shorttext:
Hemisection spinal cord injury (SCI) in preclinical models results in pathological and functional features that mimic the human condition. Chronic pain secondary to neuronal injury is actively and continuously modulated at multiple locations along the sensory neuraxis. Here, we describe how pain-processing neurons of the spinal cord process and communicate nociceptive information in terms of precisely calibrated firing patterns. We then discuss how several cell types, with a focus on 5-HTergic neurons, cause system-wide interference in nociceptive processing through novel signaling schema, thus contributing to sensory network plasticity and chronic pain.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Bryan Hains
Number of pages:
264
Published on:
2011-04-01
Stock:
Available
Category:
Clinical disciplines
Price:
79.00 €
Keywords:
nociception, pain, Spinal cord injury, hyperexcitability, cells, Transplantation, Therapy, paralysis, therapy

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