Bookcover of Biocompatible Nonionic Microemulsions
Booktitle:

Biocompatible Nonionic Microemulsions

Formulation and Characterisation Approach

LAP LAMBERT Academic Publishing (2012-12-11 )

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ISBN-13:

978-3-8454-3467-4

ISBN-10:
3845434678
EAN:
9783845434674
Book language:
English
Blurb/Shorttext:
Rigorous regulations in pharmaceutical industry urge for more sophisticated approaches that could be used for design and characterisation of drug delivery systems. Microemulsions are promissing carriers of active pharmaceutical ingredients. Researchers in this field are focused on development of biocompatible microemulsions stabilised by nonionic surfactants mixtures. The efficiency of tensides mixtures for microemulsion formation, their microstructure, solubilisation capacity, and mechanisms of drug release are scarcely investigated. This book provides a new formulation strategy of microemulsions based on multicomponent surfactant mixtures by conducting phase behaviour study and developing arteficial neural network models suitable for microemulsion area modeling. There is also demenstrated evaluation of colloidal microstructure, drug solubilisation capacity, and in vitro drug release mechanism of a model drug ibuprofen. The comprehensive approach for nonionic microemulsion carriers design may be useful to formulators in pharmaceutical, cosmetic and food industries as well as for anyone else who are interested in research and application of such complex systems.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Ljiljana Djekic
Number of pages:
212
Published on:
2012-12-11
Stock:
Available
Category:
Pharmacy
Price:
79.00 €
Keywords:
Ibuprofen, phase behaviour, Nonionic Surfactants, in vitro drug release, biocompatible microemulsions, arteficial neural network, microemulsion microstructure, drug solubilisation capacity, PEG-8 caprylic/capric glycerides

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