Beneficial of Medical Plant to overcoming Bacterial Resistance

Antibacterial Activity of Ethanolic Extract of Ocimum basilicum Leaves Against Diarrhea Caused by E. coli in Rats

LAP LAMBERT Academic Publishing (2015-01-20 )

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ISBN-13:: 978-3-659-64808-3
ISBN-10:: 3659648086
EAN:: 9783659648083
Book language:: English
Blurb/Shorttext:: The present study was carried out to investigate the antibacterial activity of Ocimum basilicum ethanolic extract in-vitro and in-vivo by inducing diarrhea in rat which was caused by oral administration of pathogenic Escherichea coli. From the results obtained, it could be concluded that ethanolic extract of O.B leaves at dose 200 mg/kg. BW. was more effective and safe in comparison with antibacterial agent and other O.B dose, this anti-diarrheal activity of O.B ethanolic extract may be due to its constituents of secondary metabolites alkaloids like (hyoscyamine and scopolamine), phenols like (Catechol and pyrogallol), tannins, saponins, flavonoids like (Quercetin and Epicatechin), steroids and terpenoids, that are responsible for the antibacterial activity with different mechanisms of action.
Publishing house:: LAP LAMBERT Academic Publishing
Website:: https://www.lap-publishing.com/
By (author) :: Sarhan Rashid, Orooba M.S. Ibrahem
Number of pages:: 104
Published on:: 2015-01-20
Stock:: Available
Category:: Veterinary medicine
Price:: 54.90 €
Keywords:: diarrhea, Escherichia coli, Ocimum basilucum, Antibiotic resistance, Antimicrobial activity