Bookcover of Attenuation of Th1 Cell Immune Response
Booktitle:

Attenuation of Th1 Cell Immune Response

-Through Galectin-9-TIM-3 Interactions Inhibits Autoimmune Diabetes in NOD Mice

金琅学术出版社 (2016-07-22 )

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ISBN-13:

978-3-639-82608-1

ISBN-10:
3639826086
EAN:
9783639826081
Book language:
English
Blurb/Shorttext:
Galectin-9, widely expressed in many tissues, regulates Th1 cells and induces their apoptosis through its receptor, T-cell immunoglobulin mucin 3 (TIM-3), which is mainly expressed on terminally differentiated Th1 cells. Type 1 diabetes is a Th1-dominant autoimmune disease that specifically destroys insulin-producing cells. To suppress the Th1 immune response in the development of autoimmune diabetes, we overexpressed galectin-9 in NOD mice by injection of a plasmid encoding galectin-9.
Publishing house:
金琅学术出版社
Website:
https://www.goldenlight-publishing.com
By (author) :
Feng-Cheng Chou
Number of pages:
76
Published on:
2016-07-22
Stock:
Available
Category:
Medicine
Price:
19.80 €
Keywords:
pathogenic Th1 cells, autoimmune diabetes, Galectin-9, TIM-3, type I diabetes

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