Bookcover of Application of NQS in Pharmaceutical Analysis
Booktitle:

Application of NQS in Pharmaceutical Analysis

Analysis of Pharmaceuticals Amine using NQS -Cephalosporin, Fluoroquinolones, -Cardiovascular & Antimalarialdrugs

LAP LAMBERT Academic Publishing (2012-06-03 )

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ISBN-13:

978-3-659-14708-1

ISBN-10:
3659147087
EAN:
9783659147081
Book language:
English
Blurb/Shorttext:
This book demonstrates the potential of 1,2-Naphthoquinone-4-sulphonic acid sodium salt (NQS) as an analytical reagent for the analysis of pharmaceutical drugs bearing amine group in their pharmaceutical formulation. Simple, fast and reliable spectrophotometric methods were developed and validated for the determination of various pharmaceuticals bearing amine group ,cephalosporin, fluoroquinolones, cardiovascular drugs and antimalarial. Different variables affecting the reactions between the NQS and the drug bearing amine group such as pH, concentration of NQS, temperature, and reaction time were carefully studied and optimized. The methods developed were validated with respect to accuracy, precision, linearity, selectivity, sensitivity, limit of detection, and limit of quantification according to the International Conference of Harmonization (ICH) guidelines for validation of analytical procedures. The proposed methods were successfully applied to the determination of each drug in its pharmaceutical dosage form with a high accuracy and precision, without the need for complex sample preparation such as extraction steps prior to the drug analysis. and without interference from
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Abdalla Elbashir
Number of pages:
116
Published on:
2012-06-03
Stock:
Available
Category:
Pharmacy
Price:
49.00 €
Keywords:
fluoroquinolones, Spectrophotometry, Cephalosporins, NQS, cardiovascular drugs and antimalarial

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