Bookcover of Activated Nitriles in Heterocyclic Synthesis
Booktitle:

Activated Nitriles in Heterocyclic Synthesis

Studies on the Chemistry of N-(cyanoacetyl) aminoantipyrine & antipyrinylhydrazonomalononitrile

LAP LAMBERT Academic Publishing (2012-04-23 )

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ISBN-13:

978-3-8484-8787-5

ISBN-10:
384848787X
EAN:
9783848487875
Book language:
English
Blurb/Shorttext:
The introduction part in this work presents a systematic and comprehensive survey of the methods of preparation and the chemical reactivity of cyanoacetamide derivatives. These compounds are important intermediates for the synthesis of a variety of otherwise difficulty accessible, synthetically useful and novel heterocyclic systems, for this reason. We focused our aim to use starting material possess a wide variety of potentially useful applications including biological, clinical and pharmacological areas. We found 4-aminoantipyrine (4AAP) possess the previously mentioned properties, so we used it as precursor to prepare polyfunctionally substituted heterocyclic compounds. The work divided into two parts, the first part discussed the utilization of N-(cyanoacetyl) aminoantipyrine for building new heterocyclic compounds. The second part discussed the formation of novel heterocyclic rings via the use of antipyrinylhydrazonomalononitrile as starting material. Both two parts followed by antimicrobial screening for the selected prepared compounds.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Ramy Rabie Shafek Ahmed, A Fadda, Etman, Bondock
Number of pages:
188
Published on:
2012-04-23
Stock:
Available
Category:
Organic chemistry
Price:
68.00 €
Keywords:
heterocycles, Pyrimidine, Pyridine, Thiophene, Thiazole, pyrazole, cyanoacetanilide, pyridazine, Aminoantipyrine.

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