Bookcover of Aberrant Phenotype in Malignant Lymphoma
Booktitle:

Aberrant Phenotype in Malignant Lymphoma

Clinical and Biological Significance

LAP LAMBERT Academic Publishing (2012-10-18 )

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ISBN-13:

978-3-659-26773-4

ISBN-10:
3659267732
EAN:
9783659267734
Book language:
English
Blurb/Shorttext:
Peripheral B- and T-cell lymphomas may express immune phenotypes which differ from those seen on normal peripheral B- and T-cells, so-called aberrant phenotypes that may consist of atypical cross-lineage antigen expression, asynchronous-antigen expression, antigen overexpression, tissue-restricted phenotypes, abnormal maturation pathways. In our studies we reported two different types of aberrant phenotypes in malignant lymphoma.The aberrant expression of B-and T-cell markers may be not incidental but could be indicative of antigenic phenotype that has not been recognized previously. These cases with aberrant phenotypes require genotypic analysis for lineage assignment and studies of such cases may be helpful to better elucidate whether they represent a distinct entity with clinical, immunophenotypic and molecular characteristics or just an incidental phenomenon during malignant transformation.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Alessandro D'Amuri, Federica Floccari
Number of pages:
64
Published on:
2012-10-18
Stock:
Available
Category:
Other
Price:
49.00 €
Keywords:
aberrant lymphoma; immunohistochemical and molecular analysis

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