Portada del libro de Synthesis and antimicrobial activity of Phthalimide derivatives
Título del libro:

Synthesis and antimicrobial activity of Phthalimide derivatives

Antimicrobial activity of new molecules

LAP LAMBERT Academic Publishing (2012-04-22 )

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ISBN-13:

978-3-8454-1838-4

ISBN-10:
3845418389
EAN:
9783845418384
Idioma del libro:
Inglés
Notas y citas / Texto breve:
A series of novel phthalimide derivatives (SV 1-8) have been synthesized and evaluated for antimicrobial activity. The target compounds were prepared by fusion of glycine with phthalic anhydride at 150-155 ºC to afford 2-(1, 3- dioxoisoindolin-2-yl) acetic acid. The compound 2-(1, 3-dioxoisoindolin-2-yl) acetic acid was treated with thionyl chloride in chloroform to afford 2-(1, 3-dioxoisoindolin-2-yl) acetyl chloride which was further treated with substituted phenols in presence of anhydrous potassium carbonate in dry acetone yielded the final compounds (SV1-8). The structures of the target compounds were characterized on the basis of their m.p., TLC, IR and 1H-NMR data. All the target compounds were evaluated for antibacterial and antifungal activity.
Editorial:
LAP LAMBERT Academic Publishing
Sitio web:
https://www.lap-publishing.com/
Por (autor):
Shakir Saleem, Jahangir Alam, Imran Kazmi
Número de páginas:
108
Publicado en:
2012-04-22
Stock:
Disponible
Categoría:
Monografías
Precio:
49.00 €
Palabras clave:
Antibacterial activity, Antifungal activity, New molecules

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